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December 7, 2017, Gmax Biopharm LLC., a clinical stage biopharmaceutical company focusing on therapeutic antibody development targeting GPCRs, today announced that it has dosed the first patient in the phase 2 clinical trial of GMA102 in Australia and New Zealand. GMA102 is a humanized antibody against GLP-1R for type 2 diabetes and obesity.
The phase 2, randomized, placebo-controlled, double-blinded, semi-sequential dose escalation study, is designed to further evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of GMA102 in Type 2 Diabetes patients.
Top line results of the phase 2 study are expected in mid of 2018.